I'm a huge fan of "travel backpacks" which differ than hiking backpacks in that they are front loading, have zippers that go most of the way around, have lockable zippers and have a detachable day pack. Hiking backpacks on the other hand, may provide a better weight suspension but they are mostly toploading which is annoying if you have to rummage to the bottom of your bag to find something and then re-pack it all (especially somewhere in public where you don't want to display all the contents of your bag).
I've travelled with a 77 L backpack which is entirely too large (I'm about 5'4'' in height). If you have larger, you pack more = way to freakin heavy!
Cons of a large backpack: its heavy. Having the pack on your back is one thing, but constantly lifting it up at least 50-100 centimetres in the air (to put it on your back) is another.
More cons: the bigger it is, the more likely that your pack will have to go at the bottom of the bus or on top. If you're in an area where there is a lot of theft, you want to keep your backpack with you at all times (being able to put your leg over the back, or stick your foot through a shoulder strap).
However, just to be fair: cons of a smaller backpack = can't carry as much, can't buy as many souvenirs along your travels (unless you decide to mail it all back home), what you bring has to be very efficient, practical and useful.
Questions to ask yourself:
Are you a packrat? Are there many things you absolutely cannot live without? Are you going to want to purchase many things along the way of your travels?
If you do decide to go with a smaller pack, but realize you are a packrat (as I am)... things you can do to cut down on weight:
for sleepsheets... try to find a silk one instead of cotton (its lighter and compresses smaller).
find a sleeping bag (if you need one) that compresses to the size of maybe 2 loafs of bread instead of 10 loaves of bread (sorry.. not sure what else would work as an analogy).
Bring clothing/footwear that serves multiple purposes. ie. sarong (towel, blanket, fashion attire), chaco/teva sandals (great for shower, water sports, all around walking),
select clothing that is quickdry - will dry quickly in a few hours (usually synthetically made v. something made out of cotton).
Try to pack clothing that is layerable and thinner v. bulky sweaters that will take up lots of room (same goes with sweatpants).
Try to figure out what can be bought locally in the country you're in (not too expensive) v. what cannot be easily found in that country (certain drugs from home, tampons, condoms, etc). If its found locally, don't bother packing it along.
Hope this helps. Feel free to e-mail me if you have further unanswered questions.
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